Reversing Age-Related Hair Loss in Women
Hair loss isn’t exclusively a male problem – approximately 50% of all women over the age of 50 experience a similar condition, referred to as female androgenetic alopecia. Symptoms in women are generally less severe than those experienced by men, appearing as an overall thinning of hairs across the top of the head, and the gradual loss of hairs down the center part-line of the scalp. The reason women experience milder symptoms is due to hormonal differences – women produce significantly lower amounts of testosterone than men (about 95% less on average). Women also produce lower levels – about 60 percent less than men – of the enzyme 5α-reductase that converts testosterone into DHT.
Additionally, women produce higher levels of another enzyme, aromatase (estrogen synthase), that converts testosterone into the female hormone, estradiol. While males also produce small amounts of aromatase, research has shown that aromatase levels in the frontal and rear scalp follicles in women are four to six times higher than in men, which is why women rarely lose hair in these areas.
Human Trials – Alopecia Totalis
Following the positive outcome of the male pattern baldness trials, the researchers began to test the new formula on several women diagnosed with Alopecia totalis, a condition that causes lymphocytes to attack hair follicles during the growth phase of the hair cycle. In extreme cases, Alopecia totalis can result in the total loss of hair on the head, face, eyebrows and eyelashes within six months. Full recovery is rare, and even with effective treatment, new hair growth in patients with alopecia totalis is often incomplete.
• CASE 1: Ms. Y., 26-years-old, was diagnosed with Alopecia totalis in July, 2006. Early signs of hair loss were attributed to stress from work and school, but within two months all of the hair on her head, eyebrows included, had dropped out. Conventional treatment failed to address the problem, and when Ms. Y. entered the trial all that remained were a few black strands in the occipital region (Fig. 1). After taking PriaPlex for six months, new hair began to appear (Fig. 2). After two years of treatment, Ms. Y. fully regrew her hair. (Fig. 3) Two years after completing treatment, Ms. Y. reports that her hair is still full and strong, with good volume and no further loss.CASE 2: Ms. L. had previously tried every other available treatment to reverse her hair loss, but all failed. She had been completely bald for eight years by the time she enrolled in the trial. After taking the formula for six months, there was no improvement in her condition and Ms. L. decided to discontinue treatment (see note).
CASE 3: Ms. H., 28-years-old, experienced serious, unexplained hair loss in the summer of 2007, and within two months had lost all of her hair, including eyebrows (Fig. 4). Ms. H. began to experience new hair growth within two months of taking PriaPlex (Fig. 5). Significantly, Ms. H. reported that her previously white hair was growing back in her natural color, black (Fig. 6). The researchers expected that newly grown hair would not regain its original color for at least 2 or 3 full hair cycles, so her case was especially interesting. Ms. H. reached a near-full recovery in six months. Unfortunately, Ms. H. stopped taking PriaPlex after her initial treatment and experienced a relapse after six months.NOTE: Each of the cases of Alopecia Totalis discussed above resulted in completely different outcomes: the first was successful, the second ineffective, and the third a relapse. Note that in the third case, researchers had previously predicted that newly grown hair would not regain its original color for at least two or three full hair cycles, so her case was especially interesting.
SUMMARY: From these cases the scientists concluded that the longer one waits before beginning treatment with PriaPlex, the greater the chances for permanent and unrecoverable damage to hair follicles. The scientists also concluded that early treatment at the first signs of hair loss improves the probability of total recovery. Additionally, treatments have to be continued until the underlying condition is eliminated to prevent a future recurrence of hair loss.